Description

(25R)-15,15-Ethylenedithio-3β-Acetyloxy-5α-Spirostane CAS NO 24742-80-1 is a high-purity, synthetic steroidal intermediate characterized by its specific dithioacetal and acetylated functional groups. This compound is of critical importance for its role as a key building block in the synthesis of complex pharmaceutical agents, particularly in the development of steroidal drugs and hormone analogs. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in advanced organic synthesis, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of steroidal active pharmaceutical ingredients (APIs) and hormone analogs.
• Organic Synthesis Research: Used as a specialized building block in academic and industrial research for constructing complex molecular architectures with defined stereochemistry.
• Process Chemistry Development: Employed in the development and optimization of scalable synthetic routes for steroidal compounds in pilot plants and manufacturing settings.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Applied in studies investigating steroidal pathways, receptor interactions, and the development of novel therapeutic agents.

Basic Information

Product Name	(25R)-15,15-Ethylenedithio-3β-Acetyloxy-5α-Spirostane
CAS No.	24742-80-1
Molecular Formula	C₃₁H₄₈O₄S₂
Molecular Weight	548.84 g/mol
Synonyms	(25R)-15,15-Ethylenedithio-3β-acetoxy-5α-spirostane; 3β-Acetoxy-15,15-ethylenedithio-5α-spirostane; 15,15-Ethylenedithio-3β-acetoxy-5α-spirostane; Tigogenin 3-acetate 15,15-ethylenedithio ketal; Tigogenin acetate ethylenedithioketal; 5α-Spirostan-3β-ol, 15,15-ethylenedithio-, 3-acetate, (25R)-; Steroidal dithioacetal intermediate
EINECS	Contact for details

Quality Control

Our (25R)-15,15-Ethylenedithio-3β-Acetyloxy-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.