Description

(25R)-12,12-Ethylenedithio-5α-Spirostane CAS NO 24742-76-5 is a high-purity steroidal intermediate characterized by its specific 12,12-ethylenedithio protective group. This compound is of critical importance in the synthesis of complex steroid-based pharmaceuticals, where it serves as a key building block to ensure stereochemical control and functional group manipulation. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including hormone modulators and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of bioactive steroid molecules and active pharmaceutical ingredients (APIs).
• Steroid Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and creating steroid analogs with potential therapeutic value.
• Process Chemistry: Employed in scale-up and optimization of manufacturing routes for steroid-based drugs, leveraging the protective group for selective reactions.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(25R)-12,12-Ethylenedithio-5α-Spirostane
CAS No.	24742-76-5
Molecular Formula	C29H46O3S2
Molecular Weight	506.81 g/mol
Synonyms	(25R)-Spirostan-12,12-ethylenedithio-3-ol; 12,12-Ethylenedithio-(25R)-spirostan-3β-ol; 5α-Spirostane-3β-ol, 12,12-ethylenedithio-, (25R)-; (25R)-12,12-Ethylenedithiospirostan-3β-ol; 12,12-(Ethylenedithio)-5α-spirostan-3β-ol (25R)-; Ethylenedithio Protective Group Steroid Intermediate; CAS 24742-76-5
EINECS	Contact for details

Quality Control

Our (25R)-12,12-Ethylenedithio-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert conditions if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.