Description

(25R)-5α-Spirost-20-Ene CAS NO 24742-74-3 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of various bioactive steroid compounds. Its defined stereochemistry and structural integrity are critical for ensuring the efficacy and purity of downstream pharmaceutical and research products. This compound is essential for manufacturers and research institutions in the pharmaceutical, agrochemical, and life science sectors requiring a reliable, high-quality building block for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial starting material for the synthesis of steroidal drugs, including corticosteroids, hormones, and other therapeutic agents.
• Research & Development: Used in academic and industrial laboratories for studying steroid biosynthesis, metabolism, and for developing new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of certain plant growth regulators and bioactive agrochemicals.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, GC-MS, or NMR method development and validation.
• Fine Chemical Production: A building block for the manufacture of other high-value, specialized steroidal fine chemicals and derivatives.

Basic Information

Product Name	(25R)-5α-Spirost-20-Ene
CAS No.	24742-74-3
Molecular Formula	C27H42O3
Molecular Weight	414.62 g/mol
Synonyms	(25R)-Spirost-5-en-3β-ol; (25R)-5α-Spirost-20(22)-en-3β-ol; Tigogenin; (25R)-5α-Spirosten-3β-ol; Neotigogenin; 3β-Hydroxy-(25R)-5α-spirost-20(22)-ene; 5α,25R-Spirost-20(22)-en-3β-ol; Tigogenin (25R isomer)
EINECS	Contact for details

Quality Control

Our (25R)-5α-Spirost-20-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for related substances and residual solvents. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your stringent specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.