Description

2-((3R,5R,7R)-Adamantan-1-Yl)Ethan-1-Amine Hydrochloride is a high-purity, chiral adamantane derivative used as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its rigid, three-dimensional adamantane core provides unique steric and electronic properties, making it invaluable for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for its role in creating molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the adamantane structure confers stability and specific biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, dendrimers, and metal-organic frameworks (MOFs) with tailored properties.
• Catalyst Ligand Development: The amine functionality and chiral centers make it a candidate for designing novel asymmetric catalysts.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme mechanisms and protein interactions.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of complex, high-value organic molecules.

Basic Information

Product Name	2-((3R,5R,7R)-Adamantan-1-Yl)Ethan-1-Amine Hydrochloride
CAS No.	24644-08-4
Molecular Formula	C12H22ClN
Molecular Weight	215.76 g/mol
Synonyms	1-Adamantylethylamine Hydrochloride; (1-Adamantyl)ethylamine Hydrochloride; 2-(1-Adamantyl)ethanamine Hydrochloride; (R,R,R)-2-Adamantan-1-ylethylamine Hydrochloride; 1-(2-Aminoethyl)adamantane Hydrochloride; Adamantane-1-ethylamine Hydrochloride; NSC 163022; 2-(Tricyclo[3.3.1.13,7]decan-1-yl)ethan-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-((3R,5R,7R)-Adamantan-1-Yl)Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.