Description

D-Glucitol, 1-Thio- is a sulfur-containing derivative of the sugar alcohol glucitol (sorbitol), characterized by the replacement of a hydroxyl group with a thiol group. This unique structure makes it a valuable chiral building block and intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the life sciences, agrochemical, and specialty chemical industries for applications requiring specific stereochemistry and functional group manipulation.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for nucleoside analogs and other bioactive compounds.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and metabolic pathway research due to its structural similarity to natural sugars.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal complexation in asymmetric synthesis.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty surfactants, chelating agents, and other high-value sulfur-functionalized chemicals.
• Agrochemical Development: Investigated as an intermediate in the synthesis of novel crop protection agents with potential new modes of action.

Basic Information

Product Name	D-Glucitol, 1-Thio-
CAS No.	24531-57-5
Molecular Formula	C₆H₁₄O₅S
Molecular Weight	198.24 g/mol
Synonyms	1-Thio-D-glucitol; 1-Deoxy-1-mercapto-D-glucitol; 1-Thio-D-sorbitol; D-1-Thioglucitol; 1-SH-D-Glucitol; 1-Mercapto-1-deoxy-D-glucitol; (2S,3R,4R,5R)-1,2,3,4,5,6-Hexanehexol-1-thiol
EINECS	Contact for details

Quality Control

Our D-Glucitol, 1-Thio- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. For long-term storage, consider storing under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.