Description

2-Cyano-n-(4-Bromophenyl)-Acetamide is a specialized organic compound featuring both cyano and bromophenyl functional groups, making it a versatile intermediate for advanced chemical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and amide functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators that require a halogenated aromatic core.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic semiconductors or non-linear optical (NLO) materials, due to its electron-withdrawing groups.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) or covalent inhibitors for studying enzyme function.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing advanced colorants and functional dyes with specific light-absorption properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.

Basic Information

Item	Detail
Product Name	2-Cyano-n-(4-Bromophenyl)-Acetamide
CAS No.	24522-26-7
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	2-Cyano-N-(4-bromophenyl)acetamide; (4-Bromophenyl)carbamoylacetonitrile; 4'-Bromo-2-cyanoacetanilide; Acetamide, 2-cyano-N-(4-bromophenyl)-; N-(4-Bromophenyl)-2-cyanoacetamide; 2-Cyanoacet-4'-bromoanilide; α-Cyano-4-bromoacetanilide; 4-Bromo-α-cyanoacetanilide
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-n-(4-Bromophenyl)-Acetamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets high-purity requirements for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.