Description

1-Chloro-3-Hydroxyacetone is a versatile bifunctional organic compound featuring both a reactive chloro and a hydroxy group on a short acetone backbone. This unique structure makes it a valuable chemical building block and alkylating agent for the synthesis of more complex molecules. It is primarily utilized in the research and production of pharmaceuticals, agrochemicals, and specialty fine chemicals where its dual functionality enables efficient synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators, leveraging its reactivity as an alkylating agent.
• Fine Chemical Building Block: Employed in organic synthesis for creating heterocyclic compounds, chiral auxiliaries, and other complex molecular architectures.
• Cross-linking Agent: Functions in polymer chemistry to modify or create polymers with specific properties for coatings or resins.
• Bioconjugation Reagent: Useful in biochemical research for labeling or modifying proteins and other biomolecules.
• Laboratory Research: Serves as a standard reagent in academic and industrial R&D for methodological development and exploratory synthesis.

Basic Information

Product Name	1-Chloro-3-Hydroxyacetone
CAS No.	24423-98-1
Molecular Formula	C3H5ClO2
Molecular Weight	108.52 g/mol
Synonyms	3-Chloro-2-hydroxy-1-propanone; 3-Chloro-2-oxopropyl alcohol; 3-Chloro-2-oxopropanol; 1-Chloro-3-hydroxy-2-propanone; Chlorohydroxyacetone; 2-Hydroxy-3-chloroacetone; α-Chlorohydroxyacetone; 3-Chloro-2-hydroxypropanone
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Hydroxyacetone is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Ensure containers are kept upright and properly sealed when not in use to minimize evaporation and exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.