Description

(R)-5,6,7,8-Tetrahydro-3,5-Dimethylnaphtho[2,3-B]Furan-4,9-Dione is a high-purity, chiral naphthoquinone derivative with significant synthetic utility. This compound serves as a critical chiral building block and synthetic intermediate for the development of complex organic molecules, particularly in pharmaceutical research. It is essential for chemists and R&D departments in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate its specific stereochemistry and functional groups into target compounds.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds targeting specific biological pathways.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex, enantiomerically pure molecules.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides, herbicides, or plant growth regulators with enhanced efficacy.
• Material Science: Potential intermediate for synthesizing specialized organic electronic materials or ligands for metal-organic frameworks (MOFs).
• Academic & R&D: Used in university and corporate research laboratories for methodological studies in organic chemistry and total synthesis projects.
• Fine Chemical Production: Intermediate in the multi-step synthesis of other high-value, specialty fine chemicals and flavors/fragrances.

Basic Information

Product Name	(R)-5,6,7,8-Tetrahydro-3,5-Dimethylnaphtho[2,3-B]Furan-4,9-Dione
CAS No.	24393-84-8
Molecular Formula	C₁₄H₁₄O₃
Molecular Weight	230.26 g/mol
Synonyms	(R)-3,5-Dimethyl-5,6,7,8-tetrahydronaphtho[2,3-b]furan-4,9-dione; (R)-Menadione furan derivative; (R)-Tetrahydronaphthofurandione; (R)-THNFD; (R)-5,6,7,8-Tetrahydro-3,5-dimethyl-4,9-dioxonaphtho[2,3-b]furan; (R)-Vitamin K3 analogue; (R)-2,3-Dihydro-3,5-dimethylbenzo[g]benzofuran-4,9-dione
EINECS	Contact for details

Quality Control

Our (R)-5,6,7,8-Tetrahydro-3,5-Dimethylnaphtho[2,3-B]Furan-4,9-Dione is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.