Description

L-Ribose is a naturally occurring, biologically active enantiomer of the pentose sugar ribose, distinguished by its specific stereochemistry. This high-purity chiral building block is essential for synthesizing nucleoside analogs, antiviral agents, and other fine chemicals where stereochemical integrity is critical. It serves as a key intermediate for pharmaceutical research, diagnostic reagent development, and advanced material science applications requiring precise molecular configuration.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of L-nucleoside analogs and antiviral drugs (e.g., Lamivudine analogs).
• Biochemical Research: Used in enzymology studies and as a substrate for investigating carbohydrate metabolism and enzyme specificity.
• Diagnostic Reagents: Employed in the production of specialized reagents and kits for clinical diagnostics and bioassays.
• Chiral Synthesis: Serves as a versatile chiral pool synthon for the asymmetric synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• Glycochemistry: Building block for the preparation of L-configuration carbohydrates, glycoconjugates, and glycomimetics.
• Cosmetic & Nutraceutical R&D: Investigated for potential applications in advanced cosmetic formulations and specialized nutraceutical products.

Basic Information

Product Name	L-Ribose
CAS No.	24259-59-4
Molecular Formula	C5H10O5
Molecular Weight	150.13 g/mol
Synonyms	L-(-)-Ribose; (2S,3S,4S)-2,3,4,5-Tetrahydroxypentanal; L-Ribopyranose; L-Ribofuranose; (-)-Ribose; L-Ribo-pentose; L-Rib
EINECS	246-110-7

Quality Control

Our L-Ribose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive quality assurance, with specifications typically meeting or exceeding research-grade and pharmaceutical intermediate requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay, enantiomeric purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent moisture absorption and caking.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-20.0° to -23.0° (c=1 in H2O)
Enantiomeric Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.