Description

[7S,(-)]-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8α-Diol is a complex spirocyclic organic compound with a unique molecular architecture, serving as a critical chiral intermediate or reference standard in advanced synthetic chemistry. Its value lies in its precise stereochemistry and functional groups, which are essential for constructing sophisticated pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and alkaloid-based drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex alkaloids and potential drug candidates targeting neurological pathways.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances in pharmaceutical R&D.
• Asymmetric Synthesis: Employed in academic and industrial research to study and develop new asymmetric catalytic reactions due to its intricate stereogenic centers.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies in the search for new bioactive molecules.
• Biochemical Research: Potential use as a tool compound for investigating specific enzyme interactions or receptor binding studies.

Basic Information

Item	Detail
Product Name	[7S,(-)]-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8α-Diol
CAS No.	24181-78-0
Molecular Formula	C22H23NO5
Molecular Weight	381.42 g/mol
Synonyms	(-)-Spirobrassinin; (7S)-3',4',6,8-Tetrahydro-6'-methoxy-2'-methylspiro[7H-indeno[4,5-d][1,3]dioxole-7,1'(2'H)-isoquinoline]-7',8α-diol; Spirobrassinol; 7S-Spirobrassinin; 7S-(-)-Spirobrassinin; Brassinin spiro-derivative; Spirocyclic brassinin analog
EINECS	Contact for details

Quality Control

Our [7S,(-)]-3',4',6,8-Tetrahydro-6'-Methoxy-2'-Methylspiro[7H-Indeno[4,5-D]-1,3-Dioxole-7,1'(2'H)-Isoquinoline]-7',8α-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by advanced techniques like HPLC and NMR, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which could affect stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.