Description

[S,(+)]-1,4-Diamino-2-Butanol is a high-purity, chiral amino alcohol building block of significant importance in asymmetric synthesis. Its value lies in its dual functional groups, which make it a versatile intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications such as chiral ligand synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of enantiomerically pure drugs, particularly those targeting neurological and cardiovascular diseases.
• Chiral Ligand & Catalyst Synthesis: Used to prepare ligands for asymmetric catalysis, enabling highly selective chemical transformations in fine chemical production.
• Peptidomimetic Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs for drug discovery programs.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme mechanisms and biological pathways.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Agrochemical Synthesis: Utilized in the research and development of chiral active ingredients for advanced crop protection agents.

Basic Information

Product Name	[S,(+)]-1,4-Diamino-2-Butanol
CAS No.	24177-21-7
Molecular Formula	C4H12N2O
Molecular Weight	104.15 g/mol
Synonyms	(2S)-1,4-Diaminobutan-2-ol; (S)-(+)-1,4-Diamino-2-butanol; (S)-1,4-Diamino-2-butanol; (S)-2-Hydroxy-1,4-butanediamine; L-1,4-Diamino-2-butanol; (S)-2-Hydroxybutane-1,4-diamine; S(+)-1,4-Diamino-2-butanol; (2S)-2-Hydroxy-1,4-butanediamine
EINECS	Contact for details

Quality Control

Our [S,(+)]-1,4-Diamino-2-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. Due to its hygroscopic and easily oxidized nature, prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.