Description

2-(Bromomethyl)-2-(2-Methylphenyl)-1,3-Dioxolane is a specialized brominated acetal derivative, serving as a versatile and reactive synthetic intermediate. Its core value lies in its ability to introduce both a bromomethyl functionality and a protected carbonyl equivalent into target molecules, enabling complex organic transformations. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities. Its unique structure makes it valuable for constructing complex heterocycles and chiral building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring chiral centers or complex ether/ketone functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for nucleophilic substitution reactions, Grignard reagent formation, and as a precursor for aldehydes via deprotection.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-(Bromomethyl)-2-(2-Methylphenyl)-1,3-Dioxolane
CAS No.	24169-43-5
Molecular Formula	C12H15BrO2
Molecular Weight	271.15 g/mol
Synonyms	2-(Bromomethyl)-2-(o-tolyl)-1,3-dioxolane; o-Methylbenzaldehyde Ethylene Acetal Bromomethyl Derivative; 2-(2-Methylphenyl)-2-(bromomethyl)-1,3-dioxolane; α-(Bromomethyl)-o-tolualdehyde Ethylene Acetal; 1,3-Dioxolane, 2-(bromomethyl)-2-(2-methylphenyl)-; Bromomethyl o-tolyl ketone ethylene ketal
EINECS	Contact for details

Quality Control

Our 2-(Bromomethyl)-2-(2-Methylphenyl)-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.