Description

(-)-2-(3,4-Dihydroxyphenyl)-5,9-Dihydroxy-8-(2-Hydroxypropyl)-4H,10H-Benzo[1,2-B:3,4-B']Dipyran-4,10-Dione is a high-purity, complex polyphenolic compound with significant biological activity. This compound matters for its role as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on developing new drugs, especially in areas like oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with potential therapeutic applications.
• Biochemical Research: Used as a reference standard or probe in life science research to study biological pathways, enzyme interactions, and cellular mechanisms.
• Natural Product Synthesis: Serves as a key chiral precursor in the total synthesis of complex natural products and their analogs for structure-activity relationship (SAR) studies.
• High-Value Fine Chemical Production: Employed in the manufacture of specialized fine chemicals where high purity and specific stereochemistry are required.
• Academic Research: Utilized in university and institutional laboratories for advanced organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	(-)-2-(3,4-Dihydroxyphenyl)-5,9-Dihydroxy-8-(2-Hydroxypropyl)-4H,10H-Benzo[1,2-B:3,4-B']Dipyran-4,10-Dione
CAS No.	23986-34-7
Molecular Formula	C22H18O9
Molecular Weight	426.37 g/mol
Synonyms	(-)-Epicatechin Gallate; (-)-ECG; L-Epicatechin gallate; L-ECG; Epicatechin-3-gallate; Benzo[1,2-b:3,4-b']dipyran-4,10-dione derivative; 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate (related tautomeric form)
EINECS	Contact for details

Quality Control

Our (-)-2-(3,4-Dihydroxyphenyl)-5,9-Dihydroxy-8-(2-Hydroxypropyl)-4H,10H-Benzo[1,2-B:3,4-B']Dipyran-4,10-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.