Description

4-Chloro-8-(Trifluoromethyl)Quinoline CAS NO 23779-97-7 is a versatile halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a valuable intermediate for creating compounds with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or cancer, leveraging the quinoline core's bioactivity.
• Agrochemical Synthesis: Used to develop advanced pesticides and herbicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysts, or specialty polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
• Ligand and Catalyst Preparation: Can be utilized to synthesize complex chelating ligands for metal catalysis in fine chemical production.

Basic Information

Product Name	4-Chloro-8-(Trifluoromethyl)Quinoline
CAS No.	23779-97-7
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	4-Chloro-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)-4-chloroquinoline; 4-Chloro-8-trifluoromethylquinoline; Quinoline, 4-chloro-8-(trifluoromethyl)-; 23779-97-7; 4-Chloro-8-trifluoromethyl-quinoline; 4-Chloro-8-(trifluoromethyl)chinolin
EINECS	Contact for details

Quality Control

Our 4-Chloro-8-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.