Description

8-(Trifluoromethyl)Quinolin-4-Ol is a high-purity fluorinated quinoline derivative, a versatile and valuable building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture to develop novel active ingredients. It is primarily utilized in the pharmaceutical and agrochemical industries for the research and development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Acts as a monomer or functional additive in the creation of specialty polymers, liquid crystals, and organic light-emitting diodes (OLEDs) due to its electron-withdrawing properties.
• Chemical Synthesis: Functions as a versatile ligand in catalysis and a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Diagnostic Reagents: Employed in the design and synthesis of fluorescent probes and biomarkers for biochemical assays and imaging.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-4-Ol
CAS No.	23779-96-6
Molecular Formula	C₁₀H₆F₃NO
Molecular Weight	213.16 g/mol
Synonyms	4-Hydroxy-8-(trifluoromethyl)quinoline; 8-(Trifluoromethyl)-4-quinolinol; 4-Quinolinol, 8-(trifluoromethyl)-; 8-Trifluoromethylquinolin-4-ol; Quinolin-4-ol, 8-(trifluoromethyl)-; 8-Trifluoromethyl-4-hydroxyquinoline; 8-CF3-Quinolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.