Description

2-(3H-Imidazol-4-Yl)Ethanamine Hydrochloride is an important organic salt derivative of histamine, valued for its role as a versatile synthetic intermediate and building block in advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring a stable, high-purity form of the histamine moiety for pharmaceutical and biochemical applications. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), diagnostic reagents, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of histamine receptor ligands, H1/H2/H3/H4 antagonists, and other bioactive molecules targeting the central nervous and immune systems.
• Biochemical Research: Used in enzymatic studies, receptor binding assays, and as a precursor for labeled compounds (e.g., fluorescent or radioactive tracers) in life science research.
• Diagnostic Reagent Manufacturing: Serves as a core component in the production of reagents for allergy testing and histamine-related diagnostic kits.
• Fine Chemical Synthesis: Employed in the preparation of complex heterocyclic compounds, chiral auxiliaries, and specialty chemicals for agrochemical and material science applications.
• Reference Standard: Supplied as a high-purity certified reference material (CRM) for quality control and analytical method validation in pharmaceutical laboratories.

Basic Information

Product Name	2-(3H-Imidazol-4-Yl)Ethanamine Hydrochloride
CAS No.	23758-34-1
Molecular Formula	C5H10ClN3
Molecular Weight	147.61 g/mol
Synonyms	Histamine Dihydrochloride (common misnomer, often refers to the dihydrochloride salt); 4-(2-Aminoethyl)imidazole Hydrochloride; 2-(1H-Imidazol-4-yl)ethanamine Hydrochloride; 2-(4-Imidazolyl)ethylamine Hydrochloride; 4-(2-Aminoethyl)-1H-imidazole Hydrochloride; 1H-Imidazole-4-ethanamine, Hydrochloride; Ceplene (as the active pharmaceutical ingredient); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 2-(3H-Imidazol-4-Yl)Ethanamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for pharmaceutical and research use. Certificates of Analysis (COA) with detailed batch-specific results are provided and traceable to in-house reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.