Description

2-Chloro-4-Amino-6,7-Dimethoxyquinazoline is a high-purity, synthetically versatile quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure makes it an essential intermediate for the development of complex, high-value pharmaceutical compounds and specialty fine chemicals. This product is primarily targeted at research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other targeted cancer therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold for medicinal chemistry and the discovery of new bioactive molecules.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and advanced material precursors.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and novel compound library synthesis.

Basic Information

Product Name	2-Chloro-4-Amino-6,7-Dimethoxyquinazoline
CAS No.	23680-84-4
Molecular Formula	C11H12ClN3O2
Molecular Weight	253.69 g/mol
Synonyms	4-Amino-2-chloro-6,7-dimethoxyquinazoline; 2-Chloro-6,7-dimethoxyquinazolin-4-amine; 6,7-Dimethoxy-2-chloroquinazolin-4-ylamine; PD 153035 Hydrochloride Intermediate; EGFR Inhibitor Intermediate; Tyrphostin AG 1517 Analog; Quinazoline, 4-amino-2-chloro-6,7-dimethoxy-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Amino-6,7-Dimethoxyquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.