Description

5-Chloro-1,6-Naphthyridine is a versatile and high-value heterocyclic building block with significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials who require reliable, high-purity chemical intermediates.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Serves as a building block for creating organic semiconductors, ligands for catalysis, and photoactive materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & R&D: A fundamental reagent for methodological development in organic chemistry and heterocyclic compound research.
• Custom Synthesis: Acts as a starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Chloro-1,6-Naphthyridine
CAS No.	23616-32-2
Molecular Formula	C8H5ClN2
Molecular Weight	164.59 g/mol
Synonyms	5-Chloro-1,6-naphthyridine; 1,6-Naphthyridine, 5-chloro-; 5-Chloro-1,6-diazanaphthalene; 5-Chloro[1,6]naphthyridine; 23616-32-2 (CAS); 5-Chloro-1,6-naphthyridin; 5-Cl-1,6-Naphthyridine
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,6-Naphthyridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.