Description

1,6-Naphthyridin-5(6H)-One is a high-purity heterocyclic organic compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique fused-ring structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science: Building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Synthesis: Versatile scaffold for medicinal chemistry and combinatorial library synthesis in drug discovery programs.
• Academic & R&D: Essential reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and corporate R&D labs.

Basic Information

Product Name	1,6-Naphthyridin-5(6H)-One
CAS No.	23616-31-1
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	5(6H)-1,6-Naphthyridinone; 1,6-Naphthyridin-5-ol; 5-Hydroxy-1,6-naphthyridine; 1,6-Naphthyridin-5-one; 5-Oxo-5,6-dihydro-1,6-naphthyridine; 5,6-Dihydro-1,6-naphthyridin-5-one; 1,6-Naphthyridin-5(6H)-one; 23616-31-1 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our 1,6-Naphthyridin-5(6H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.