Description

Hexyl Nicotinate is a synthetic ester derivative of nicotinic acid (Vitamin B3) and hexanol, known for its vasodilatory and skin-penetrating properties. This compound is valued for its ability to enhance microcirculation and facilitate the transdermal delivery of active ingredients. It is a key functional ingredient sought by manufacturers in the cosmetic, personal care, and pharmaceutical industries for advanced topical formulations.

Application

• Topical Cosmetic & Skincare Products: Primarily used as a vasodilator and penetration enhancer in anti-aging serums, creams, and lotions designed to improve skin tone and reduce the appearance of fine lines.
• Hair Care Formulations: Incorporated into scalp treatments and hair growth solutions to stimulate blood flow to hair follicles and enhance the efficacy of other active compounds.
• Pharmaceutical Topicals: Employed in medicated creams and ointments to increase the absorption of therapeutic agents through the skin barrier.
• Sports & Wellness Gels: Used in warming gels and muscle relief formulations for its local circulatory effects.
• Cosmeceutical R&D: Serves as a critical intermediate or active ingredient in the development of new dermal delivery systems and cosmetic actives.

Basic Information

Product Name	Hexyl Nicotinate
CAS No.	23597-82-2
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	Hexyl nicotinate; Nicotinic acid hexyl ester; Hexyl pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, hexyl ester; NSC 523773; Hexyl ester of nicotinic acid; Nikethamide analog
EINECS	Contact for details

Quality Control

Our Hexyl Nicotinate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for cosmetic and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with GMP principles and relevant ICH guidelines for ingredient traceability and safety.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided. For long-term storage, consider an inert atmosphere (e.g., nitrogen blanket).

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.485 - 1.495
Specific Gravity	1.020 - 1.050

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.