Description

(2R,4'Aα,5S)-3',4,4',4A',5,5',6',7',8',8A'-Decahydro-6'β-Hydroxy-5-(2-Hydroxyethyl)-2'α,5',8'Aβ-Trimethylspiro[Furan-2(3H),1'(2'H)-Naphthalene]-5,5'α-Dimethanol is a complex, high-purity spirocyclic compound of significant interest in advanced organic synthesis. Its intricate stereochemistry and functional groups make it a valuable chiral building block and intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and manufacturers of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug molecules, particularly in steroid-like or terpenoid-based therapeutic areas.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex molecular architectures in academic and industrial research.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development of new catalytic systems due to its defined stereocenters.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals, including flavors, fragrances, and agrochemicals.
• Reference Standard: Supplied as a high-purity analytical standard for method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	(2R,4'Aα,5S)-3',4,4',4A',5,5',6',7',8',8A'-Decahydro-6'β-Hydroxy-5-(2-Hydroxyethyl)-2'α,5',8'Aβ-Trimethylspiro[Furan-2(3H),1'(2'H)-Naphthalene]-5,5'α-Dimethanol
CAS No.	23554-81-6
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	6'-Hydroxy-5-(2-hydroxyethyl)-2',5',8'a-trimethylspiro[furan-2(3H),1'(2'H)-naphthalene]-5,5'-dimethanol, (2R,4'aα,5S)-decahydro-; 6'-Hydroxy-5-(2-hydroxyethyl)-2',5',8'a-trimethylspiro[furan-2(3H),1'(2'H)-naphthalene]-5,5'-dimethanol, (2R,4'aα,5S)-decahydro-; Spiro[furan-2(3H),1'(2'H)-naphthalene]-5,5'-dimethanol, 3',4,4',4a',5,5',6',7',8',8a'-decahydro-6'-hydroxy-5-(2-hydroxyethyl)-2',5',8'a-trimethyl-, (2R,4'aα,5S)-; (2R,4'aα,5S)-3',4,4',4a',5,5',6',7',8',8a'-Decahydro-6'-hydroxy-5-(2-hydroxyethyl)-2',5',8'a-trimethylspiro[furan-2(3H),1'(2'H)-naphthalene]-5,5'-dimethanol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development projects with custom purity grades and analytical data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.