Description

(R)-(-)-1,2,3,4-Tetrahydro-1-Naphthylamine CAS NO 23357-46-2 is a chiral amine derivative of tetralin, serving as a crucial chiral building block and resolving agent in advanced organic synthesis. Its value lies in its ability to impart stereochemical control in the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active pharmaceutical ingredients (APIs) and other high-value chiral molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly for central nervous system (CNS) and cardiovascular targets.
• Chiral Resolving Agent: Used to separate racemic mixtures of carboxylic acids and other compounds via diastereomeric salt formation.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Employed in the research and development of chiral pesticides and herbicides.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological development in synthetic organic chemistry and stereochemistry studies.

Basic Information

Product Name	(R)-(-)-1,2,3,4-Tetrahydro-1-Naphthylamine
CAS No.	23357-46-2
Molecular Formula	C10H13N
Molecular Weight	147.22 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-1-naphthylamine; (R)-(-)-1-Amino-1,2,3,4-tetrahydronaphthalene; (R)-1,2,3,4-Tetrahydro-1-naphthalenamine; (R)-1,2,3,4-Tetrahydro-naphthalen-1-ylamine; (R)-Tetrahydronaphthylamine; (R)-THNA; (R)-1-Tetralinamine; (1R)-1,2,3,4-Tetrahydro-1-naphthalenamine
EINECS	Contact for details

Quality Control

Our (R)-(-)-1,2,3,4-Tetrahydro-1-Naphthylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination by HPLC, to ensure it meets the stringent requirements for chiral intermediates. Certificates of Analysis (COA) detailing specific results for all critical parameters are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.