Description

1-(4-Nitro-Phenyl)-Cyclopropanecarboxylic Acid is a high-purity organic compound featuring a cyclopropane ring substituted with a carboxylic acid and a para-nitrophenyl group, making it a valuable synthon for complex molecular architectures. Its primary commercial value lies in its role as a critical building block in pharmaceutical research and fine chemical synthesis, particularly for developing active pharmaceutical ingredients (APIs) and advanced materials. This intermediate is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce constrained three-membered ring systems into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the cyclopropane moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers with specific electronic or structural properties.
• Academic & Industrial R&D: A versatile building block for methodological chemistry research, including cyclopropanation studies and heterocycle formation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	1-(4-Nitro-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	23348-99-4
Molecular Formula	C10H9NO4
Molecular Weight	207.18 g/mol
Synonyms	4-Nitrobenzenecyclopropanecarboxylic Acid; 1-(4-Nitrophenyl)cyclopropanecarboxylic Acid; 1-(p-Nitrophenyl)cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 1-(4-nitrophenyl)-; p-Nitrophenylcyclopropanecarboxylic Acid; (4-Nitrophenyl)cyclopropanecarboxylic Acid; 4-Nitro-alpha,α-cyclopropylbenzenecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(4-Nitro-Phenyl)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical development and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen) to prevent oxidation and moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.