Description

6-Methylene-1,4-Dioxaspiro[4.5]Decane is a versatile spirocyclic acetal compound, serving as a crucial building block in advanced organic synthesis. Its unique bicyclic structure, featuring a reactive exocyclic methylene group, makes it an invaluable precursor for constructing complex molecular frameworks. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of spirocyclic drug candidates targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of novel pesticides and herbicides, leveraging its spirocyclic core for enhanced biological activity.
• Fragrance & Flavor Chemistry: Acts as a precursor for synthetic musks and other complex aroma chemicals due to its stable, oxygenated bicyclic structure.
• Polymer Science: Serves as a monomer or cross-linking agent for creating specialty polymers with unique thermal and mechanical properties.
• Organic Synthesis Building Block: Employed in Diels-Alder reactions and other cycloadditions to construct intricate polycyclic systems in total synthesis projects.
• Ligand and Catalyst Development: Utilized to create novel chelating spiro ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Methylene-1,4-Dioxaspiro[4.5]Decane
CAS No.	23153-81-3
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	6-Methylenespiro[1,3-dioxolane-2,1'-cyclohexane]; 1,4-Dioxaspiro[4.5]dec-6-ene; 6-Methylene-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane], 6-methylene-; 6-Methylidene-1,4-dioxaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our 6-Methylene-1,4-Dioxaspiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.