Description

1,4-Dioxaspiro[4.4]Nonane-6-Carboxylic Acid, Ethyl Ester is a high-purity spirocyclic building block and chiral synthon of significant value in advanced organic synthesis. Its unique fused ring system and ester functionality make it a versatile precursor for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, including potential central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its spirocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic and R&D: A valuable tool in methodological chemistry research for studying ring-forming reactions and stereoselective transformations.
• Material Science Precursor: Potential use in synthesizing monomers for specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-6-Carboxylic Acid, Ethyl Ester
CAS No.	23153-73-3
Molecular Formula	C11H18O4
Molecular Weight	214.26 g/mol
Synonyms	Ethyl 1,4-Dioxaspiro[4.4]nonane-6-carboxylate; 6-Carbethoxy-1,4-dioxaspiro[4.4]nonane; Ethyl 6-Oxaspiro[2.5]octane-5-carboxylate (related structure); Spirocyclic ethyl ester; 1,4-Dioxaspiro[4.4]nonane-6-carboxylic acid ethyl ester; NSC 334916; AS-81058; Ethyl 1,4-dioxaspiro[4.4]nonane-6-carboxylic acid ester
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.4]Nonane-6-Carboxylic Acid, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.