Description

2-Bromo-5-Nitro-4-Picoline is a halogenated and nitrated pyridine derivative, serving as a versatile and high-value synthetic building block in advanced organic chemistry. Its core value lies in its dual functionalization, which enables precise molecular construction for complex target molecules. This intermediate is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific halogenated heterocyclic cores.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive bromo and nitro groups for further functionalization.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Bromo-5-Nitro-4-Picoline
CAS No.	23056-47-5
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	4-Methyl-2-bromo-5-nitropyridine; 2-Bromo-5-nitro-4-methylpyridine; 5-Nitro-2-bromo-4-picoline; 2-Bromo-5-nitro-4-methylpyridine; 4-Picoline, 2-bromo-5-nitro-; 2-Bromo-5-nitro-4-methylpyridine; 4-Methyl-5-nitro-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Nitro-4-Picoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.