Description

(1S)-2α-Phenylcyclopropane-1α-Carboxylic Acid CAS NO 23020-18-0 is a high-purity chiral cyclopropane derivative, a crucial building block in advanced organic synthesis. Its rigid, three-membered ring structure and defined stereochemistry make it an invaluable intermediate for constructing complex molecules with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potent drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the cyclopropane moiety enhances biological activity and stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective reactions.
• Material Science: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Academic & Process Chemistry: Employed in methodological development and scale-up studies for complex organic transformations.

Basic Information

Product Name	(1S)-2α-Phenylcyclopropane-1α-Carboxylic Acid
CAS No.	23020-18-0
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(1S)-2-Phenylcyclopropanecarboxylic Acid; (1S)-2-Phenylcyclopropane-1-carboxylic Acid; (1S)-2-Phenylcyclopropanecarboxylic Acid; (S)-2-Phenylcyclopropanecarboxylic Acid; (S)-2-Phenylcyclopropane-1-carboxylic Acid; (S)-PCA; (S)-Phenylcyclopropanecarboxylic Acid; (-)-trans-2-Phenylcyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

We supply (1S)-2α-Phenylcyclopropane-1α-Carboxylic Acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and impurity profile is provided with each batch. We adhere to strict in-house quality standards to meet the demanding requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.