Description

8-Bromo-6-Fluoroquinoline is a high-purity halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactivity sites for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antibacterial and anticancer agents, leveraging the quinoline core structure.
• Agrochemical Synthesis: Used in the development of new-generation fungicides and herbicides, where the bromo and fluoro substituents modulate biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and luminescent compounds.
• Chemical Biology: Employed as a probe or labeling reagent due to its halogen atoms, which are amenable to further cross-coupling reactions.
• Academic & R&D: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	8-Bromo-6-Fluoroquinoline
CAS No.	22960-18-5
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	6-Fluoro-8-bromoquinoline; 8-Bromo-6-fluoroquinoline; Quinoline, 8-bromo-6-fluoro-; 22960-18-5; 8-Br-6-F-quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.