Description

(1Alpha,3Beta,5Beta,7Alpha)-8,8-Dichloro-1,4,4-Trimethyltricyclo[5.1.0.03,5]Octane is a high-purity, advanced bicyclic organic intermediate characterized by its unique, rigid tricyclic framework and geminal dichloro substitution. This compound matters for its role as a critical synthon in the synthesis of complex, high-value molecules, offering a versatile scaffold for constructing sterically defined structures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers developing performance materials like advanced polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its rigid structure can contribute to unique biological activity.
• Material Science Research: Acts as a precursor for developing specialty polymers, resins, and liquid crystalline materials with specific thermal or optical properties.
• Organic Synthesis & Methodology: Employed in academic and industrial R&D to study novel cyclopropanation reactions and ring-strain chemistry.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for creating complex, musky, or amber-type odorants due to its polycyclic nature.
• Catalyst Ligand Development: The defined three-dimensional structure makes it a candidate for developing chiral ligands in asymmetric catalysis.

Basic Information

Product Name	(1Alpha,3Beta,5Beta,7Alpha)-8,8-Dichloro-1,4,4-Trimethyltricyclo[5.1.0.03,5]Octane
CAS No.	22819-70-1
Molecular Formula	C11H16Cl2
Molecular Weight	219.15 g/mol
Synonyms	8,8-Dichloro-1,4,4-trimethyltricyclo[5.1.0.03,5]octane; (1α,3β,5β,7α)-8,8-Dichloro-1,4,4-trimethyltricyclo[5.1.0.03,5]octane; 1,4,4-Trimethyl-8,8-dichlorotricyclo[5.1.0.03,5]octane; Dichlorotrimethyltricyclooctane; Tricyclo[5.1.0.03,5]octane, 8,8-dichloro-1,4,4-trimethyl-; Bicyclic dichloro intermediate
EINECS	Contact for details

Quality Control

Our (1Alpha,3Beta,5Beta,7Alpha)-8,8-Dichloro-1,4,4-Trimethyltricyclo[5.1.0.03,5]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.