Description

4-Amino-5,6,7,8-Tetrahydronaphthalen-1-Ol CAS NO 22658-04-4 is a high-purity, functionalized tetrahydronaphthalene derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique fused-ring structure with both amino and phenolic hydroxyl groups makes it a versatile precursor for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of central nervous system (CNS) active drugs, cardiovascular agents, and other therapeutic compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymeric materials due to its electron-donating properties.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized naphthalene-based dyes and colorants.
• Academic and R&D Laboratories: A valuable compound for methodological studies in organic chemistry, including new cyclization and functionalization reactions.

Basic Information

Product Name	4-Amino-5,6,7,8-Tetrahydronaphthalen-1-Ol
CAS No.	22658-04-4
Molecular Formula	C₁₀H₁₃NO
Molecular Weight	163.22 g/mol
Synonyms	5-Amino-1,2,3,4-tetrahydro-6-naphthol; 5-Amino-6-hydroxy-1,2,3,4-tetrahydronaphthalene; 4-Amino-5,6,7,8-tetrahydro-1-naphthalenol; 6-Hydroxy-5-amino-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydro-5-amino-6-naphthol; 5-Amino-1,2,3,4-tetrahydro-6-hydroxynaphthalene; 4-Amino-1,2,3,4-tetrahydro-5-naphthol
EINECS	Contact for details

Quality Control

Our 4-Amino-5,6,7,8-Tetrahydronaphthalen-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable supply for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.