Description

1-O,2-O:3-O,4-o-Bis(1-Methylethylidene)-6-Deoxy-β-L-Arabino-5-Hexenopyranose is a high-purity, protected carbohydrate derivative, specifically a diacetonide of a 6-deoxy hexenose. This compound is a critical chiral building block and synthetic intermediate valued for its defined stereochemistry and protective groups, which enable selective chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, nucleoside analogs, and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for nucleoside-based drugs and antiviral agents.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, insecticides, and fungicides with specific stereochemical requirements.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials where precise molecular architecture is essential.
• Glycochemistry Research: Acts as a protected sugar derivative for studying glycosylation reactions, carbohydrate chemistry, and enzyme mechanisms.
• Process Chemistry & Scale-up: Provides a reliable starting material for optimizing synthetic routes from laboratory to pilot and commercial scale production.
• Academic & Institutional Research: Supports investigative studies in organic synthesis, medicinal chemistry, and chemical biology within universities and R&D institutes.

Basic Information

Product Name	1-O,2-O:3-O,4-o-Bis(1-Methylethylidene)-6-Deoxy-β-L-Arabino-5-Hexenopyranose
CAS No.	22618-03-7
Molecular Formula	C14H22O5
Molecular Weight	270.32 g/mol
Synonyms	6-Deoxy-1,2:3,4-di-O-isopropylidene-β-L-arabino-hex-5-enopyranose; Diacetone-6-deoxy-β-L-arabino-hex-5-enopyranose; 1,2:3,4-Di-O-isopropylidene-6-deoxy-β-L-arabino-hex-5-enopyranose; 6-Deoxy-1,2:3,4-di-O-isopropylidene-β-L-galactopyranose (related isomer); Protected L-Arabinose derivative; Diacetonide of 6-deoxy-L-arabino-hexenose
EINECS	Contact for details

Quality Control

Our 1-O,2-O:3-O,4-o-Bis(1-Methylethylidene)-6-Deoxy-β-L-Arabino-5-Hexenopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications including assay, chiral purity, and impurity profiles. Our quality commitment supports applications requiring research-grade to GMP-standard materials, with documentation available for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.