Description

(1R)-1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-Pentenyl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde CAS NO 22571-65-9 is a complex, high-purity sesquiterpene derivative with a defined stereochemistry. This compound is valued for its role as a critical chiral intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise, high-quality building blocks for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex terpenoid or azulene-based structures.
• Advanced Organic Synthesis: Serves as a versatile building block for constructing complex natural product analogs and molecules with specific stereochemical configurations.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its unique molecular scaffold.
• Fragrance & Flavor Chemistry: Potential precursor for synthesizing novel aroma chemicals due to its sesquiterpene backbone, which is common in many natural fragrances.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and medicinal chemistry.

Basic Information

Item	Details
Product Name	(1R)-1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-Pentenyl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde
CAS No.	22571-65-9
Molecular Formula	C₂₂H₃₄O₄
Molecular Weight	362.50 g/mol
Synonyms	1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-penten-1-yl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde; (1R)-1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-pentenyl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde; (1R)-1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-pentenyl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde; Azulene derivative CAS 22571-65-9; Sesquiterpene aldehyde intermediate
EINECS	Contact for details

Quality Control

Our (1R)-1,2,3,3A,4,7,8,8Aβ-Octahydro-1-[(Z)-5-Hydroxy-3-Hydroxymethyl-3-Pentenyl]-1α-Hydroxymethyl-2α,5-Dimethyl-3Aβ-Azulenecarbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.