Description

D-Glucopyranose, 1-Thio- is a sulfur-containing derivative of glucose, where a thiol group replaces the hydroxyl at the anomeric carbon, making it a key thioglycoside building block. This compound is valued for its role as a versatile intermediate in the synthesis of complex carbohydrates, glycoconjugates, and enzyme inhibitors. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and biochemical studies.

Application

• Glycoscience Research: A fundamental precursor for synthesizing thioglycosides and other carbohydrate mimetics used in studying glycosylation and carbohydrate-protein interactions.
• Pharmaceutical Intermediates: Serves as a critical building block in the development of novel therapeutics, including antiviral agents and enzyme inhibitors.
• Chemical Biology Probes: Used to create labeled or modified sugars for probing metabolic pathways and cellular processes.
• Glycoconjugate Synthesis: Employed in the preparation of neoglycoconjugates for vaccine development and diagnostic applications.
• Enzymology Studies: Acts as a substrate or inhibitor for glycosidases and glycosyltransferases in mechanistic studies.

Basic Information

Product Name	D-Glucopyranose, 1-Thio-
CAS No.	22566-82-1
Molecular Formula	C6H12O5S
Molecular Weight	196.22 g/mol
Synonyms	1-Thio-β-D-glucopyranose; 1-Thio-D-glucose; β-D-Glucopyranosyl mercaptan; 1-S-Glucose; 1-Thio-β-D-glucopyranose; Thioglucose; D-1-Thioglucose
EINECS	Contact for details

Quality Control

Our D-Glucopyranose, 1-Thio- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.