Description

Octahydro-2H-Quinolizin-1-Ol is a saturated bicyclic amino alcohol of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable chiral building block for constructing complex nitrogen-containing heterocycles, which are core structures in many active pharmaceutical ingredients. Pharmaceutical researchers and fine chemical manufacturers need it for developing new therapeutic agents, particularly in the areas of alkaloid synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent bioactive molecules and active pharmaceutical ingredients (APIs).
• Alkaloid Synthesis: Serves as a fundamental scaffold for constructing complex natural product analogs and novel alkaloid derivatives.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the design of new drug candidates targeting neurological and other disorders.
• Fine Chemical Production: Acts as a specialized intermediate for manufacturing high-value, low-volume chemicals with specific stereochemical requirements.

Basic Information

Product Name	Octahydro-2H-Quinolizin-1-Ol
CAS No.	22525-60-6
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	1-Hydroxyoctahydro-2H-quinolizine; 1-Quinolizidinol; Octahydro-1-hydroxy-2H-quinolizine; 1-Hydroxyquinuclidine (common misnomer, structurally related); 1-Azabicyclo[4.3.0]nonan-9-ol; 1-Quinolizidinol, octahydro-; 22525-60-6; NSC 163044
EINECS	Contact for details

Quality Control

Our Octahydro-2H-Quinolizin-1-Ol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.