Description

(1R)-1,1Aβ,2,4,5,6,6A,7Aβ-Octahydro-1,6β,6Aβ-Trimethyl-1α,2Aα-Methano-2Ah-Cyclopropa[B]Naphthalene-3,7-Dione is a complex, high-purity tricyclic diterpenoid derivative with a unique cyclopropane-fused structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its defined stereochemistry and functional groups. It is primarily sought by research institutions and fine chemical manufacturers engaged in the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to construct intricate polycyclic frameworks due to its rigid, functionalized core.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and testing of new stereoselective catalytic reactions.
• Natural Product Analog Synthesis: Used to create synthetic analogs of complex natural diterpenoids for structure-activity relationship (SAR) studies.
• Material Science Research: Potential monomer or precursor for the development of specialized polymers with unique thermal or optical properties.
• Reference Standard: High-purity grade is supplied as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	(1R)-1,1Aβ,2,4,5,6,6A,7Aβ-Octahydro-1,6β,6Aβ-Trimethyl-1α,2Aα-Methano-2Ah-Cyclopropa[B]Naphthalene-3,7-Dione
CAS No.	22471-61-0
Molecular Formula	C15H18O2
Molecular Weight	230.30 g/mol
Synonyms	1,6β,6aβ-Trimethyl-1α,2aα-methano-2ah-cyclopropa[b]naphthalene-3,7-dione; (1R)-1,1aβ,2,4,5,6,6a,7aβ-Octahydro-1,6β,6aβ-trimethyl-1α,2aα-methano-2ah-cyclopropa[b]naphthalene-3,7-dione; Tricyclic Diterpenoid Dione; Cyclopropanaphthalenedione derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for batches intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.