Description

3-Hydroxyphenylacetamide is a versatile aromatic amide compound with a phenolic hydroxyl group, serving as a key intermediate in advanced organic synthesis. Its bifunctional structure makes it valuable for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), fine chemicals, and specialty polymers who require a reliable, high-purity building block.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its phenolic and amide functionalities.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other colorants, where the hydroxyl group facilitates coupling reactions.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, such as polyamides and epoxy resins, to impart specific thermal or mechanical properties.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and proteomics research due to its structural similarity to tyrosine derivatives.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for creating complex, high-value organic molecules for various industrial applications.

Basic Information

Product Name	3-Hydroxyphenylacetamide
CAS No.	22446-41-9
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	3-Hydroxybenzeneacetamide; (3-Hydroxyphenyl)acetamide; m-Hydroxyphenylacetamide; 3-Hydroxy-α-toluamide; 2-(3-Hydroxyphenyl)acetamide; 3-Acetamidophenol (tautomeric form); NSC 403697; m-Tyramine amide
EINECS	Contact for details

Quality Control

Our 3-Hydroxyphenylacetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed when not in use to minimize contact with moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.