Description

(9S)-9-(6-Ethenyl-4-Methoxy-1,3-Benzodioxol-5-Yl)-7,8,9,10-Tetrahydro-5-Methoxy-8-Methyl-1H-[1,3]Dioxino[5,4-F]Isoquinoline is a complex, chiral isoquinoline derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block or intermediate for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents, particularly alkaloid-based drugs.
• Neurological Research: Serves as a core structure for developing compounds that interact with specific neurotransmitter systems.
• Asymmetric Synthesis: Utilized as a chiral template or ligand in stereoselective catalytic reactions due to its complex stereochemistry.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new bioactive chemical space.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Building block for creating novel dyes, pigments, or other specialty chemicals with complex fused-ring systems.

Basic Information

Item	Details
Product Name	(9S)-9-(6-Ethenyl-4-Methoxy-1,3-Benzodioxol-5-Yl)-7,8,9,10-Tetrahydro-5-Methoxy-8-Methyl-1H-[1,3]Dioxino[5,4-F]Isoquinoline
CAS No.	22325-07-1
Molecular Formula	C23H23NO6
Molecular Weight	409.43 g/mol
Synonyms	(-)-Glaucine; (S)-Glaucine; L-Glaucine; NSC 403169; 1,2,9,10-Tetramethoxyaporphine; (6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline; Glaucine (alkaloid); 1,2,9,10-Tetramethoxyaporphine
EINECS	Contact for details

Quality Control

Our (9S)-Glaucine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with GLP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.