Description

2-(Chloromethyl)-3-(4-Methylphenyl)Quinazolin-4(3H)-One is a specialized quinazolinone derivative, a high-value chemical intermediate prized for its reactive chloromethyl group and aromatic quinazolinone core. This compound matters for its role in facilitating the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to build novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the quinazolinone moiety is active.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialized polymers or organic electronic materials.
• Chemical Synthesis Reagent: The reactive chloromethyl group allows for further functionalization, making it a versatile reagent in organic synthesis for creating custom chemical libraries.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Item	Detail
Product Name	2-(Chloromethyl)-3-(4-Methylphenyl)Quinazolin-4(3H)-One
CAS No.	22312-80-7
Molecular Formula	C16H13ClN2O
Molecular Weight	284.74 g/mol
Synonyms	3-(p-Tolyl)-2-(chloromethyl)-4(3H)-quinazolinone; 2-(Chloromethyl)-3-(p-tolyl)-4(3H)-quinazolinone; 3-(4-Methylphenyl)-2-(chloromethyl)-4(3H)-quinazolinone; 2-Chloromethyl-3-(4-methylphenyl)-4-quinazolinone; 4(3H)-Quinazolinone, 2-(chloromethyl)-3-(4-methylphenyl)-; 2-(Chloromethyl)-3-(4-methylphenyl)quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-3-(4-Methylphenyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.