Description

Benzenesulfonyl-Difluoro-Acetic Acid is a specialized organofluorine building block featuring a reactive difluoroacetic acid moiety linked to a benzenesulfonyl group. This unique structure makes it a valuable intermediate for synthesizing novel compounds with enhanced biological activity and material properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly protease inhibitors and enzyme modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with improved efficacy.
• Material Science: Serves as a precursor for advanced polymers and specialty chemicals with unique surface properties.
• Chemical Research: A versatile reagent in organic synthesis for introducing the difluoroacetate group into complex molecules.
• Fluorinated Compound Development: Essential for creating libraries of fluorinated analogs in medicinal chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Benzenesulfonyl-Difluoro-Acetic Acid
CAS No.	22235-34-3
Molecular Formula	C8H6F2O4S
Molecular Weight	236.20 g/mol
Synonyms	α,α-Difluoro-benzenesulfonylacetic Acid; 2,2-Difluoro-2-(phenylsulfonyl)acetic Acid; Benzenesulfonyl(difluoro)acetic Acid; (Difluorophenylsulfonyl)acetic Acid; Phenylsulfonyldifluoroacetic Acid; NSC 403914; 2,2-Difluoro-2-(benzenesulfonyl)ethanoic Acid
EINECS	Contact for details

Quality Control

Our Benzenesulfonyl-Difluoro-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and IR spectroscopy. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.