Description

2-Chloro-3-Nitro-5-(Trifluoromethyl)Benzamide is a high-value, multi-functional aromatic intermediate featuring a unique trifluoromethyl group. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where its specific substitution pattern imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitro substituents.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of active pharmaceutical ingredients (APIs), particularly in scaffolds targeting various disease pathways.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Synthesis: Employed in the production of specialized dyes and pigments where the nitro and chloro groups are essential for color development and fastness.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalytic systems.

Basic Information

Product Name	2-Chloro-3-Nitro-5-(Trifluoromethyl)Benzamide
CAS No.	22227-47-0
Molecular Formula	C8H4ClF3N2O3
Molecular Weight	268.58 g/mol
Synonyms	2-Chloro-3-nitro-5-(trifluoromethyl)benzamide; Benzamide, 2-chloro-3-nitro-5-(trifluoromethyl)-; 2-Chloro-3-nitro-alpha,alpha,α-trifluoro-p-toluamide; 5-(Trifluoromethyl)-2-chloro-3-nitrobenzamide; 2-Chloro-3-nitro-5-trifluoromethylbenzamide; 3-Nitro-2-chloro-5-trifluoromethylbenzamide; 2-Chloro-3-nitro-5-(trifluoromethyl)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Nitro-5-(Trifluoromethyl)Benzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.