Description

Silver Sulfadiazine is a topical antimicrobial agent that combines the broad-spectrum antibacterial action of sulfadiazine with the antiseptic properties of silver. This compound is critically important for its efficacy in preventing and treating infections in burn wounds and other severe skin injuries. It is an essential raw material for pharmaceutical manufacturers producing topical creams and wound care products, serving the global healthcare and medical device industries.

Application

• Primary Use in Burn Wound Creams: The dominant application is as the active pharmaceutical ingredient (API) in topical antimicrobial creams for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.
• Chronic Wound Management: Used in formulations for treating ulcers, such as diabetic foot ulcers and pressure sores, where infection control is paramount.
• Surgical and Trauma Care: Incorporated into wound dressings, gels, and ointments for post-surgical sites and traumatic skin abrasions to minimize bacterial colonization.
• Veterinary Pharmaceuticals: Applied in topical preparations for treating burns, wounds, and skin infections in animals.
• Biomedical Coatings: Investigated for use in coating medical devices, such as catheters and implants, to impart antimicrobial properties and reduce biofilm formation.

Basic Information

Product Name	Silver Sulfadiazine
CAS No.	22199-08-2
Molecular Formula	C10H9AgN4O2S
Molecular Weight	357.14 g/mol
Synonyms	Silver(I) sulfadiazine; Sulfadiazine Silver Salt; Silvadene; Flamazine; Dermazin; N1-(2-Pyrimidinyl)sulfanilamide silver salt; Silver sulphadiazine; SSD
EINECS	244-877-1

Quality Control

Our Silver Sulfadiazine is manufactured under strict quality management systems. It is tested to meet relevant pharmacopeial standards (such as USP/EP) for identity, purity, and potency, ensuring it is suitable for pharmaceutical formulation. Comprehensive testing includes assay, related substances, residual solvents, and heavy metal analysis. A Certificate of Analysis (COA) is provided with each batch to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White or off-white, fine powder
Identification (IR)	Conforms to standard
Identification (Silver)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Enumeration	Meets USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.