Description

1-Acetyl-6-Bromo-1,2,3,4-Tetrahydroquinoline is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized quinoline scaffold, which serves as a critical intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a building block for organic light-emitting diodes (OLEDs) and other functional materials due to its electron-rich aromatic system.
• Academic & R&D: Employed in methodological studies for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other catalytic transformations.
• Ligand Synthesis: Useful for creating novel nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: An intermediate in the multi-step synthesis of dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	1-Acetyl-6-Bromo-1,2,3,4-Tetrahydroquinoline
CAS No.	22190-40-5
Molecular Formula	C11H12BrNO
Molecular Weight	254.13 g/mol
Synonyms	6-Bromo-1-acetyl-1,2,3,4-tetrahydroquinoline; 1-(6-Bromo-3,4-dihydro-2H-quinolin-1-yl)ethanone; N-Acetyl-6-bromo-1,2,3,4-tetrahydroquinoline; 6-Bromo-1,2,3,4-tetrahydro-1-acetylquinoline; 6-Bromo-N-acetyl-1,2,3,4-tetrahydroquinoline; Ethanone, 1-(6-bromo-3,4-dihydro-2H-quinolin-1-yl)-; 1-Acetyl-6-bromotetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 1-Acetyl-6-Bromo-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.