Description

trans-4-Methoxycyclohexanol CAS NO 22188-03-0 is a versatile cyclohexanol derivative characterized by its methoxy substituent in the trans configuration. This compound serves as a valuable chiral intermediate and building block in advanced organic synthesis, prized for its defined stereochemistry and functional group compatibility. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereocenters into complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring stereochemical control.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where specific isomerism impacts biological activity.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for mesogens and other specialty organic materials due to its rigid cyclohexane ring and ether functionality.
• Fragrance & Flavor Chemistry: Employed as an intermediate for creating complex aroma chemicals with specific olfactory profiles.
• Asymmetric Catalyst Ligand Development: Utilized in research for constructing novel chiral ligands and organocatalysts.
• Polymer Modification: Acts as a monomer or modifier in specialty polymer synthesis to alter physical properties.

Basic Information

Product Name	trans-4-Methoxycyclohexanol
CAS No.	22188-03-0
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	trans-4-Methoxycyclohexan-1-ol; (1r,4r)-4-Methoxycyclohexanol; 4-Methoxycyclohexanol, trans-; 4-Methoxycyclohexanol (major isomer); p-Methoxycyclohexanol; Cyclohexanol, 4-methoxy-, trans-; 1,4-cis-4-Methoxycyclohexanol; 4-Methoxy-1-cyclohexanol
EINECS	Contact for details

Quality Control

Our trans-4-Methoxycyclohexanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and isomer content are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (trans isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.