Description

6-O-Benzyl-D-Glucose is a key protected monosaccharide derivative, widely utilized as a versatile chiral building block in organic synthesis. Its primary value lies in providing a selectively masked glucose scaffold, enabling complex carbohydrate and glycoconjugate construction without interference at the 6-position. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs), glycosylation reagents, and advanced intermediates.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of nucleoside analogs, antiviral drugs, and complex glycosylated natural products.
• Glycochemistry Research: Serves as a fundamental building block for constructing oligosaccharides, glycopeptides, and glycomimetics in medicinal chemistry programs.
• Carbohydrate Chemistry: Used in the selective protection and deprotection strategies for the synthesis of complex sugar derivatives and chiral auxiliaries.
• Bioconjugate Development: Employed in the creation of labeled sugars, glycopolymers, and carbohydrate-based probes for diagnostic and biochemical applications.
• Fine Chemical Synthesis: Acts as a chiral pool reagent for the asymmetric synthesis of non-carbohydrate targets requiring stereochemical control.

Basic Information

Product Name	6-O-Benzyl-D-Glucose
CAS No.	22170-16-7
Molecular Formula	C₁₃H₁₈O₆
Molecular Weight	270.28 g/mol
Synonyms	6-O-Benzyl-D-glucopyranose; D-Glucose, 6-O-benzyl-; 6-O-Benzyl-1,2,3,4-di-O-isopropylidene-D-glucopyranose (precursor related); 6-Benzyloxy-D-glucose; 6-O-(Phenylmethyl)-D-glucose; 6-O-Bn-D-Glucose; 6-O-Benzyl-α/β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 6-O-Benzyl-D-Glucose is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, optical rotation, and identity confirmation (IR, NMR). A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+50° to +55° (c=1 in H₂O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.