Description

2,4-Dichlorophenoxy Acetic Acid, [Methylene-14C] is a carbon-14 radiolabeled analog of the widely used synthetic auxin herbicide, 2,4-D. This compound is specifically designed for advanced research applications where precise metabolic and environmental fate tracking is required. It is an essential tool for scientists in agrochemical R&D, environmental toxicology, and plant physiology studies who require high-specific-activity tracers for autoradiography, mass balance studies, and degradation pathway analysis.

Application

• Agrochemical Metabolism and Degradation Studies: Used as a radiotracer to investigate the absorption, translocation, metabolism, and residue formation of 2,4-D in plants, soil, and water systems.
• Environmental Fate and Ecotoxicology Research: Enables precise tracking of herbicide degradation pathways, leaching potential, and bioaccumulation in non-target organisms under controlled laboratory conditions.
• Plant Physiology and Mode-of-Action Research: Facilitates the study of auxin transport, receptor binding, and the molecular mechanisms underlying the herbicidal activity of phenoxyacetic acids.
• Analytical Method Development and Validation: Serves as an internal standard or reference material in the development of highly sensitive LC-MS/MS, HPLC, or radio-HPLC methods for 2,4-D and its metabolites.
• Regulatory Submission Support: Provides critical data for regulatory dossiers required by agencies (e.g., EPA, EFSA) concerning the environmental behavior and safety profile of 2,4-D.

Basic Information

Product Name	2,4-Dichlorophenoxy Acetic Acid, [Methylene-14C]
CAS No.	22059-10-5
Molecular Formula	C8H6Cl2O3 (with 14C label)
Molecular Weight	~221.04 g/mol (unlabeled)
Synonyms	2,4-D-[methylene-14C]; [14C]-2,4-D; (2,4-Dichlorophenoxy)[14C]acetic acid; 2,4-Dichlorophenoxy[14C]acetic Acid; Radiolabeled 2,4-D; Carbon-14 Labeled 2,4-D; Herbicide Tracer 2,4-D; 2,4-Dichlorophenoxyacetic Acid-14C
EINECS	244-753-4 (for unlabeled compound)

Quality Control

Every batch of our radiolabeled compounds is produced and analyzed under strict quality control protocols to ensure chemical, radiochemical, and isotopic purity. Production adheres to cGMP principles where applicable for research materials. Each product is supplied with a comprehensive Certificate of Analysis (COA) detailing critical parameters such as specific activity, radiochemical purity (by radio-HPLC or radio-TLC), chemical purity (by HPLC), and solvent composition. Our QC procedures are designed to meet the stringent requirements of GLP-compliant research studies.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as supplied. For long-term storage, keep at -70°C to minimize radiolytic decomposition. Store in a designated area for radioactive materials in accordance with local radiation safety regulations. The storage area should be well-ventilated and secure.

Specification

Item	Specification
Appearance	Clear solution (color may vary)
Chemical Purity (HPLC)	≥ 95%
Radiochemical Purity (Radio-HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Concentration	0.1 mCi/mL in ethanol (or as specified)
Solvent	Ethanol or other suitable solvent
Identification (IR / NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.