Description

(R)-2,2,2-Trifluoro-1-Phenyl-Ethylamine is a high-value chiral amine building block characterized by its trifluoromethyl group and phenyl substituent. This compound is essential for introducing chirality and fluorine atoms into target molecules, which can dramatically alter their metabolic stability, lipophilicity, and binding affinity. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Asymmetric Catalyst Ligand: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Fluorine Chemistry Studies: A valuable reference standard and building block in academic and industrial research focused on fluorinated organic compounds.

Basic Information

Product Name	(R)-2,2,2-Trifluoro-1-Phenyl-Ethylamine
CAS No.	22038-85-3
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	(R)-α-(Trifluoromethyl)benzylamine; (R)-1-Phenyl-2,2,2-trifluoroethylamine; (R)-1-Phenylethylamine, 2,2,2-trifluoro-; (R)-TFMPEA; (R)-2,2,2-Trifluoro-1-phenylethanamine; (R)-1-(Trifluoromethyl)phenethylamine; (R)-Fenfluramine Impurity; (R)-Enantiomer of 2,2,2-Trifluoro-1-phenylethylamine
EINECS	Contact for details

Quality Control

Our (R)-2,2,2-Trifluoro-1-Phenyl-Ethylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.