Description

5-Nitro-1-benzofuran-2(3H)-one is a specialized nitro-substituted benzofuranone derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique fused-ring structure and nitro functionality, which make it a versatile building block for constructing complex heterocyclic systems. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials.
• Dye & Pigment Synthesis: Intermediate for creating nitro-containing heterocyclic dyes and organic pigments with specific light-absorption properties.
• Academic & Contract Research: Essential building block in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	5-Nitro-1-benzofuran-2(3H)-one
CAS No.	21997-23-9
Molecular Formula	C8H5NO4
Molecular Weight	179.13 g/mol
Synonyms	5-Nitro-2(3H)-benzofuranone; 5-Nitro-1-benzofuran-2-one; 5-Nitro-2-coumaranone; 5-Nitro-2,3-dihydro-1-benzofuran-2-one; 5-Nitro-2-hydroxybenzaldehyde; 2-Hydroxy-5-nitrobenzaldehyde (tautomer); 5-Nitrophthalide (common misnomer, related structure); 21997-23-9
EINECS	Contact for details

Quality Control

Our 5-Nitro-1-benzofuran-2(3H)-one is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.