Description

6-Chloro-1H-Quinolin-4-One is a versatile quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated quinolinone structure makes it a valuable building block for constructing complex molecules with targeted biological and material properties. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, crop protection, and functional material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with potential antimicrobial, anti-inflammatory, or anticancer activity.
• Agrochemical Research: Used as a core scaffold for developing novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, cyclizations, and functional group transformations to create complex molecular architectures.
• Material Science: Investigated as a precursor for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional materials.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	6-Chloro-1H-Quinolin-4-One
CAS No.	21921-70-0
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	6-Chloro-4-hydroxyquinoline; 6-Chloro-4-quinolinol; 4-Hydroxy-6-chloroquinoline; 6-Chloro-4(1H)-quinolinone; 6-Chloroquinolin-4-ol; 6-Chloro-1H-quinolin-4-one; 6-Chloro-4-quinolone
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Quinolin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.