Description

N4-(6-Aminopyrimidin-4-Yl)-Sulfanilamide Hcl CAS NO 21886-12-4 is a specialized sulfonamide derivative and a key pharmaceutical intermediate. This compound is valued for its precise chemical structure, which serves as a critical building block in the synthesis of more complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel sulfonamide-based therapeutic agents.
• Antimicrobial Research: Used in R&D for developing new compounds with potential antibacterial or antifungal activity.
• Enzyme Inhibition Studies: Serves as a scaffold for creating inhibitors targeting specific bacterial enzymes.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & Institutional Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR).
• Bioconjugation Chemistry: The reactive amine group allows for use in creating targeted molecular probes or conjugates.

Basic Information

Product Name	N4-(6-Aminopyrimidin-4-Yl)-Sulfanilamide Hydrochloride
CAS No.	21886-12-4
Molecular Formula	C10H11N5O2S • HCl
Molecular Weight	297.75 g/mol
Synonyms	4-Amino-N-(6-aminopyrimidin-4-yl)benzenesulfonamide hydrochloride; Sulfanilamide, N4-(6-amino-4-pyrimidinyl)-, monohydrochloride; 6-Amino-4-(4-aminobenzenesulfonamido)pyrimidine hydrochloride; 4-Amino-N-(6-amino-4-pyrimidinyl)benzenesulfonamide HCl; N1-(6-Aminopyrimidin-4-yl)sulfanilamide hydrochloride
EINECS	Contact for details

Quality Control

Our N4-(6-Aminopyrimidin-4-Yl)-Sulfanilamide HCl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.