Description

6-Fluoro-4-Hydroxyquinoline is a versatile fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a fluorine atom and a hydroxyl group on the quinoline scaffold, makes it a valuable intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in developing fluorinated quinolone antibiotics and other therapeutic agents.
• Agrochemical Research: Used to create advanced active ingredients for crop protection products, leveraging the fluorine atom for improved efficacy and environmental stability.
• Material Science: Serves as a building block for functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic light-emitting diodes (OLEDs).
• Chemical Synthesis: A versatile fluorinated synthon for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Biochemical Probe Development: Utilized in designing fluorescent probes and molecular tags for biological imaging and diagnostic applications.

Basic Information

Product Name	6-Fluoro-4-Hydroxyquinoline
CAS No.	21873-50-7
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	4-Hydroxy-6-fluoroquinoline; 6-Fluoro-4-quinolinol; 6-Fluoro-4-hydroxyquinoline; 4-Quinolinol, 6-fluoro-; 6-Fluoroquinolin-4-ol; 6-Fluoro-4(1H)-quinolinone (tautomer)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Hydroxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.